Editing Edgewood Arsenal human experiments (section)

==== Anticholinesterase experiments ====
[[Anticholinesterase]]s are substances that interfere with the [[central nervous system]] and the [[peripheral nervous system]] by inhibiting [[acetylcholinesterase]] and therefore sustaining the effect of [[acetylcholine]] or [[butyrylcholine]] within the [[chemical synapse]]s,<ref>{{Cite journal |last1=Colovic |first1=Mirjana B. |last2=Krstic |first2=Danijela Z. |last3=Lazarevic-Pasti |first3=Tamara D. |last4=Bondzic |first4=Aleksandra M. |last5=Vasic |first5=Vesna M. |date=2013-04-01 |title=Acetylcholinesterase Inhibitors: Pharmacology and Toxicology |url=https://www.eurekaselect.com/article/50871 |journal=Current Neuropharmacology |volume=11 |issue=3 |pages=315–335 |doi=10.2174/1570159x11311030006 |issn=1570-159X |pmc=3648782 |pmid=24179466}}</ref> resulting in a [[cholinergic crisis]], and possibly death if untreated.<ref>{{Cite book |title=Current therapy of trauma and surgical critical care |date=2016 |publisher=Elsevier |isbn=978-0-323-07980-8 |editor-last=Asenio |editor-first=Juan A. |edition=2nd |location=Philadelphia |editor-last2=Trunkey |editor-first2=Donald D.}}</ref>

Long term side effects of exposure to [[anticholinesterase]]s, including at levels below the threshold for profound illness and death can include paralysis and [[peripheral neuropathy]],<ref>{{Cite journal |last=Morgan |first=John P. |date=1978-08-01 |title=Jamaica Ginger Paralysis |url=http://dx.doi.org/10.1001/archneur.1978.00500320050011 |journal=Archives of Neurology |volume=35 |issue=8 |pages=530–532 |doi=10.1001/archneur.1978.00500320050011 |pmid=666613 |issn=0003-9942}}</ref> [[sleep disturbance]],<ref>{{Cite journal |last1=Metcalf |first1=David R. |last2=Holmes |first2=Joseph H. |date=June 1969 |title=EEG, PSYCHOLOGICAL, AND NEUROLOGICAL ALTERATIONS IN HUMANS WITH ORGANOPHOSPHORUS EXPOSURE* |url=http://dx.doi.org/10.1111/j.1749-6632.1969.tb15857.x |journal=Annals of the New York Academy of Sciences |volume=160 |issue=1 |pages=357–365 |doi=10.1111/j.1749-6632.1969.tb15857.x |pmid=5257403 |bibcode=1969NYASA.160..357M |issn=0077-8923}}</ref> genetic mutation and cancer.<ref name=":0" /> In total, 1,406 subjects were tested with 16 agents, some of which included reactivating agents and protective agents.<ref name=":0" />